Hif 1 alpha uniprot

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August undefined, 2024

Web6 de out. de 2024 · HIF is a transcription factor that plays an essential role in the cellular response to low oxygen, orchestrating a metabolic switch that allows cells to survive in this environment. In immunity, infected and inflamed tissues are often hypoxic, and HIF helps immune cells adapt. HIF-α stabilization ca … WebBackground: HIF-1 alpha/HIF1A. This biotinylated peptide includes a sequence from human Hypoxia-Inducible Factor 1-alpha (HIF-1 alpha ) with an unmodified (non-hydroxylated) proline residue corresponding to proline 564 in UniProt Q16665. The peptide is not efficiently ubiquitinated by a VHL/Elongin B/Elongin C/CUL2/RBX complex (catalog …

HIF-1 and mechanisms of hypoxia sensing - PubMed

WebHuman HIF-1 alpha ELISA kit (ab275103) is a single-wash 90 min sandwich ELISA designed for the quantitative measurement of Human HIF-1 alpha protein in cell and tissue extracts. It uses our proprietary SimpleStep ELISA® technology. Quantitate Human HIF-1 alpha with 33.39 pg/mL sensitivity. WebWe investigated the impact of inhibiting HIF-1α transcriptional activity on cytotoxic immune cell infiltration into B16-F10 melanoma. We showed that tumors expressing a deleted form of HIF-1α displayed increased levels of NK and CD8 + effector T cells in the tumor microenvironment, which was associated with high levels of CCL2 and CCL5 ... csulb kinesiology requirements

HIF1A Negative Control Peptide, Biotin S-345-010: R&D Systems

WebMonoclonal Anti-HIF2 alpha antibody produced in mouse. clone GT125, affinity isolated ... UniProt accession no. Q16665. shipped in. wet ice. storage temp. −20°C. Gene ... Hif1a(15251) rat ... Hif1a(29560) Description. General description. Hypoxia-inducible factor-1 (HIF-1) is a 120kD basic helix-loop-helix protein that belongs to the PAS ... WebBackground: HIF-1 alpha/HIF1A. This biotinylated peptide includes a sequence from human Hypoxia-Inducible Factor 1-alpha (HIF-1 alpha ) including a 4-hydroxyline proline … Web22 de out. de 2009 · Factor inhibiting HIF-1 alpha in complex with 8-hydroxyquinoline. Factor inhibiting HIF-1 alpha in complex with 8-hydroxyquinoline. ... 1.14.11.30 … early\\u0027s flooring

HIF-1 and mechanisms of hypoxia sensing - PubMed

HIF1A protein expression summary - The Human Protein Atlas

Web17 de jan. de 2003 · The activity of the transcription factor hypoxia-inducible factor (HIF) is regulated by oxygen-dependent hydroxylation. Under normoxic conditions, hydroxylation … WebProduct Specific Information. MA1-516 detects hypoxia-inducible factor 1 alpha (HIF-1 alpha) from human, non-human primate, bovine, mouse and porcine cells. This antibody does not cross-react with ARNT or the related HIF-2 alpha. MA1-516 has been successfully used in Western blot, immunofluorescence, immunoprecipitation, immunocytochemistry ... early\\u0027s garageWeb27 de fev. de 2024 · UniProt Q16665 - HIF1A_HUMAN. Gene HIF1A Modification Unmodified View Product On Supplier's Website Request a Quote ... HIF1, BHLHE78, MOP1, PASD8, HIF-1A, HIF-1alpha, HIF1-ALPHA, HIF-1-alpha. View additional product information. Experiments from the literature. Loading published images for this product … early\u0027s food store

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Hif 1 alpha uniprot

WebHIF-1-alpha 1 publication; HIF1-alpha 1 publication. Alternative names. ARNT-interacting protein; ... 1-826: UniProt: Hypoxia-inducible factor 1-alpha: BLAST Add. Sequence: Glycosylation: 18: UniProt (Microbial infection) N-beta-linked (GlcNAc) arginine 1 publication. Sequence: R: Modified residue: 247: WebUniProt Annotation. GO Annotation. Cytoplasm 1 publication. Nucleus 2 publications. ... IPR001321 HIF-1_alpha; IPR014887 HIF-1_TAD_C; IPR021537 HIF_alpha-like; More … (Microbial infection) Upon infection by human coronavirus SARS-CoV-2, is … We'd like to inform you that we have updated our Privacy Notice to comply … UniRef - UniProt History - UniProt External Links - UniProt Gostaríamos de exibir a descriçãoaqui, mas o site que você está não nos permite. UniProt Annotation. GO Annotation. Cytoplasm 1 publication. Nucleus 2 … 1 domain 7 PTMs 3 reviewed variants 4 isoforms 32 interactions 1 disease 1 3D …

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WebGet better batch-to-batch reproducibility with a recombinant antibody. Anti-HIF-1 alpha antibody [EPR16897] (ab179483) Research with confidence – consistent and reproducible results with every batch. Long-term and scalable supply – powered by recombinant technology for fast production. Success from the first experiment – confirmed ... WebHypoxia-inducible factor 1 (HIF-1) is an oxygen-regulated transcriptional activator that plays essential roles in mammalian development, physiology and disease pathogenesis. The HIF-1 alpha subunit is subjected to oxygen-dependent ubiquitination and proteasomal degradation that is mediated by the vo …

WebA fusion protein including amino acids 530 - 825 of the mouse HIF-1 alpha protein [UniProt# Q61221]. Purification Purified by antigen-affinity chromatography Conjugation Unconjugated. RRID AB_625919 Note For laboratory use only. Not for any clinical, therapeutic, or ... Web14 de abr. de 2024 · 1 Introduction. Worldwide, colorectal cancer (CRC) is the third most lethal malignant tumor and the fourth most frequently diagnosed malignant tumor (1, 2).The global incidence and mortality of CRC are increasing because of the continuously expanding and aging of the population with no differences between the sexes ().CRC accounts for …

Web12 de ago. de 2002 · 1H2K, 1H2L, 1H2M, 1H2N. PubMed Abstract: The activity of the transcription factor hypoxia-inducible factor (HIF) is regulated by oxygen-dependent hydroxylation. Under normoxic conditions, … WebUnder hypoxic conditions, activates the transcription of over 40 genes, including erythropoietin, glucose transporters, glycolytic enzymes, vascular endothelial growth …

WebHypoxia-inducible factor-1 (HIF1) is a basic helix-loop-helix (bHLH)-PER-ARNT-sim (PAS) transcription factor that plays a role in the cellular response to hypoxia. HIF1 is a heterodimer of an HIF1-alpha and HIF1-beta subunit. During normoxia, HIF-1alpha is regulated by ubiquitination and interaction with the von-Hippel-Lindau tumor suppressor ...

Web13 de fev. de 2024 · HIF prolyl hydroxylases are oxygen sensors that regulate the stability of the hypoxia-inducible factors (HIFs) in an oxygen-dependent manner. Aragones et al. (2008) showed that loss of Phd1 expression in knockout mice lowers oxygen consumption in skeletal muscle by reprogramming glucose metabolism from oxidative to more anaerobic … csulb kinesiology transferWeb3 de jul. de 2003 · Hypoxia-inducible factor 2-alpha (HIF-2-alpha; HIF2-alpha) Member of PAS protein 2; PAS domain-containing protein 2; Gene names. Name. EPAS1. … csulb land acknowledgmentWeb19 de set. de 2012 · Identification of Cys 255 in HIF-1 as a novel site for development of covalent inhibitors of HIF-1 /ARNT PasB domain ... Identification of Cys255 in HIF-1 … early\u0027s flooringWeb8 de mai. de 2015 · Crystal Structure of the Heterodimeric HIF-1a:ARNT Complex with HRE DNA. Crystal Structure of the Heterodimeric HIF-1a: ... UniProt & NIH Common Fund … csulb leadership programWebResearch Information. HIF-1α Antibody (28b) is an IgG κ mouse monoclonal HIF-1 alpha antibody (also designated HIF1A antibody or HIF-1 alpha antibody) suitable for the … csulb last day of spring 2023Web12 de ago. de 2002 · 1H2K, 1H2L, 1H2M, 1H2N. PubMed Abstract: The activity of the transcription factor hypoxia-inducible factor (HIF) is regulated by oxygen-dependent … csulb learning agreementWebGet better batch-to-batch reproducibility with a recombinant antibody. Anti-HIF-1 alpha antibody [EPR16897] (ab179483) Research with confidence – consistent and reproducible results with every batch. Long-term and scalable supply – powered by recombinant technology for fast production. Success from the first experiment – confirmed ... csulb kleefeld contemporary