WebNuclear Factor (erythroid-derived 2)-like 2 (Nrf2) is a ubiquitously expressed, basic leucine zipper transcription factor. It regulates the expression of a variety of genes encoding proteins that play critical roles in cyto-protection, as well as the detoxification and clearance of harmful endogenous and xenobiotic substances. Web20 nov. 2024 · A key element in maintaining redox homeostasis is the “master & commander” of endogenous antioxidant production; Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) [21]. Nrf2 is a basic leucine transcription factor within the cap “n” collar family which is uncoupled from its protein cluster through electrophilic or oxidative stress.
Ethylhexadecyldimethylammonium bromide, a quaternary …
Web11 feb. 2016 · NRF2 (nuclear factor erythroid-derived 2-like 2) plays an important role in defense against oxidative stress at the cellular level. Recently, the roles of NRF2 in embryonic and adult stem cells ... WebNuclear factor, erythroid derived 2, like 2; NF-E2-related factor 2; Nuclear factor erythroid 2-related factor 2; HEBP1; NRF2; NFE2-related factor 2. Gene ID. 4780(Human) Uniprot ID. Q16236(Human) Related Products; Neural Antibodies. NeuroMab™ Anti-NRF2 Antibody, Clone N25549 (CAT#: NRZP-0922-ZP3562) dog doesn\\u0027t like me
Inhibition of nuclear factor (erythroid-derived 2)-like 2 promotes ...
WebFurthermore, inhibiting DNA methyltransferase buttressed the nuclear expression of nuclear factor (erythroid-derived 2)-like factor 2, which upregulated downstream effectors such as catalase (1.838-fold increase at 7 days, p < 0.01), superoxide dismutase 1 (1.494-fold increase at 7 days, p < 0.05), and NAD(P)H: quinone oxidoreduate-1 (1.376-fold … Web10 apr. 2024 · Accumulating evidence suggests that the down-regulation of the nuclear factor erythroid-derived 2-like 2 (Nrf2)/heme oxygenase-1 (HO-1) ... CGA: Chlorogenic acid (100 mg/kg); DOX: Doxorubicin (15 mg/kg); Nrf2: Nuclear factor erythroid 2–related factor 2; HO-1: Heme Oxygenase 1. Figure 7. Apoptotic marker in cardiac tissue. dog doesn\u0027t like crate anymore