Phenoscanner gwas database
Web11. jan 2024 · 如何使用r从phenoscanner数据库中提取gwas数据 由 失忆症发布于 2024-01-11 03:23:26 键入时，我在read.table消息中遇到错误 extract.pheno.csv (exposure = "log (eGFR creatinine)", pmidE = 26831199, ancestryE = "European", outcome = "Tanner stage", pmidO = 24770850, ancestryO = "European", file = path.noproxy) 提取数据。 请帮助我 到 … WebEnhancing brown adipose tissue (BAT) function to combat metabolic disease is a promising therapeutic strategy. A major obstacle to this strategy is that a thermoneutral environment, relevant to most modern human living conditions, deactivates
Phenoscanner gwas database
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Web30. jan 2024 · The exposure and outcome GWAS provided SNP effects and corresponding standard errors . We filtered out palindromic SNPs with intermediate allele frequencies after harmonizing exposure and outcome data . We used the PhenoScanner V2 database to detect potential pleiotropy among the SNPs included in this study . Genetic variants that … WebUntitled - Free download as PDF File (.pdf), Text File (.txt) or read online for free.
Web6. dec 2024 · A total of 465 significant associations (P<0.01) were found using GWAS analysis in PhenoScanner. rs191188930 was significantly associated with other diseases or phenotypes other than cardiotoxicity, including acute pericarditis, aortic aneurysm and dissection, other necrotizing vasculopathies, urticaria, ascites and tubulo-interstitial … WebEighteenth were significantly associated about at least the additional traits (p ≤ 5 × 10 −8) in the PhenoScanner database, especially anthropometric, vessels, ... We kept PhenoScanner GWAS connection results because an p-value < 5 × …
WebR语言MendelianRandomization包 phenoscanner函数使用说明. phenoscanner函数从R内部查询基因型-表型关联的phenoscanner数据库。. snpquery : 单核苷酸多态性的载体。. genequery : 基因名称的载体。. regionquery : 基因组区域的载体。. catalogue : 要搜索的目录（选项：None、GWAS、eQTL、pQTl ... Web24. jún 2024 · PhenoScanner is a curated database of publicly available results from large-scale genetic association studies in humans. This online tool facilitates "phenome scans", …
Web30. mar 2024 · The causal association analysis between exposure and outcome was performed using a two-sample MR analysis approach based on a publicly available genome wide association study (GWAS) database of large samples, and Cochran Q test to assess heterogeneity, and finally sensitivity analysis to verify the reliability of the causal …
WebA meta-analysis of twin studies and a Swedish population-based study estimated the heritability of schizophrenia ranged from 64% to 81%. 14,15 A large genome-wide association study (GWAS) identified 128 single nucleotide polymorphisms (SNPs) significantly associated with schizophrenia which explained approximately 3.4% of the … had cleaned him upWeb1. jan 2024 · The back-end of webTWAS is developed in the Java-based Spring Boot web framework. The front-end is developed with the VueJs framework, and the user interface uses the Element UI framework for VueJS. A MySQL database is used to rapidly retrieve curated GWAS summary statistics and TWAS-identified disease potential causal genes. had clichyWebBackground Obstructive sleep apnea (OSA) has shown to be associated with an increased risk of atrial fibrillation in observational studies. Whether this association reflect causal effect is still u... hadcock 242 tonearmWeb20. feb 2024 · Data sources. A schematic overview of the data sources, genetic instrument selection, and statistical analysis in this study is presented in Fig. 1 (panel a). Summary data on NAFLD were obtained from a large genome-wide association study (GWAS) conducted by Anstee et al., which included 1483 cases and 17,781 controls [].All NAFLD cases were … hadcm3 model downloadWeb【提示】如果想要将下载到本地的GWAS结果作为exposure在TwoSampleMR中调取，则需要进一步进行清理，具体代码请移步至公众号「遗传社科研究」推文《【MR干货】如何优 … hadcock gh 228Web15. okt 2016 · PhenoScanner is a curated database of publicly available results from large-scale genetic association studies. This tool aims to facilitate 'phenome scans', the cross-referencing of genetic variants with many phenotypes, to help aid understanding of disease pathways and biology. The database currently contains over 350 million association ... had-cleanWeb9. feb 2024 · Based on summary statistics from publicly available genome-wide association studies (GWAS) database, we detected the genetic correlation between serum 25OHD levels and DN by a two-sample Mendelian randomization (MR) analysis. brainseed testing nyc