WebJun 1, 2024 · 9578 Background: Time to treatment failure (TTF) has been suggested as a practical clinical endpoint for studies of oncologic agents using real-world evidence … WebTime to next treatment（TNT) 寛解導入療法開始日を起点とし、サルベージ治療開始まで、またはあらゆる原因による死亡までの早い方の期間とする。 サルベージ治療を開始し …
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WebFeb 22, 2024 · Time-to-next treatment (TTNT) since the date of subsequent treatments can be heterogeneously captured in trial datasets sub-mitted to FDA. It is acknowledged that TTNT is another potential RWD end point that may capture additional information includ-ing potential treatment-free intervals which have been described with immunotherapy [12]. … WebAug 17, 2024 · Time to next treatment (TTNT) is an emerging endpoint in clinical studies of primary cutaneous T-cell lymphomas (CTCL), with utility as a surrogate marker for the “duration of clinical benefit”. TTNT provides a highly clinically meaningful endpoint that uniquely reflects not only the duration of treatment efficacy on disease and symptom … trunk twister exercise
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Web独立行政法人 医薬品医療機器総合機構 WebTreatment regimens were defined as all MM chemotherapy observed within 60 days of index. Patients receiving pomalidomide and carfilzomib within 60 days of index were excluded. Time to next treatment (TTNT), a progression proxy, was defined as the addition of a new agent > 60 days from index or as treatment restart following a > 90-day therapy … WebMedian survival time: MST: 累積再発割合: Cumulative incidence of relapse: CIR: 無増悪期間: Time to progression: TTP: 治療成功期間: Time to treatment failure: TTTF: 次治療開始まで … trunk up bandana history